Detection of colorectal neoplasia with peanut-agglutinin(PNA)-reactive carbohydrate structures in rectal mucus

Colonoscopy in colorectal-cancer screening for detection of advanced neoplasia.

BACKGROUND Recommendations for colorectal-cancer screening are based solely on age and family history of cancer, not sex. METHODS We performed a cross-sectional analysis of the data from a large colonoscopy-based screening program that included 50,148 participants who were 40 to 66 years of age. People 40 to 49 years of age were eligible only if they had a family history of cancer of any type...

Local management of rectal neoplasia.

The treatment of rectal neoplasia, whether benign or malignant, challenges the surgeon. The challenge in treating rectal cancer is selecting the proper approach for the appropriate patient. In a small number of rectal cancer patients local excision may be the best approach. In an attempt to achieve two goals-cure of disease with a low rate of local failure and maintenance of function and qualit...

Computer Aided Detection of Potential Colorectal Neoplasia at CT Colonography

Cross-reactive Carbohydrate Determinant Contributes to the False Positive IgE Antibody to Peanut

Background: The importance of peanut allergy has not been well recognized in Japanese society. IgE antibody to peanut can be, however, detected in patients without clinical peanut allergy. Methods: Clinical characteristics of 14 patients (aged 1―8 years) with peanut allergy were evaluated. IgE antibodies to peanut from patients with and without clinical peanut allergy were compared with those t...

Early Detection of and Screening for Colorectal Neoplasia

There are approximately one million new cases of colorectal cancer (CRC) per year worldwide, with substantial associated morbidity and mortality. The long natural history of colorectal neoplasia affords the opportunity to use preventive measures to improve survival in this disease. Currently screening for adenomatous polyps and early-stage cancers is the best methodology for improving survival....